HGVbaseG2P study database 6 has been released with 145 additional GWA studies
New studies and annotations include:

• Studies HGVST380-511 from the NHGRI GWAS Catalog
• Studies HGVST306-315 from the 1958 British Birth Cohort (B58C)
• Direct submission HGVST379 from Yang et al (PMID:19421330)
• HGVbaseG2P curated submission HGVST378
• MeSH annotations added to all studies in HGVbaseG2P

HGVbaseG2P version 3 has been redesigned for advanced integration of association datasets.
New features include:

• Complete revamp making it easier to identify Studies and Markers of interest.
• Central search which identifies whether you are searching for a region, gene, keyword or phenotype term.
• Gene/region search which identifies association studies which used significant markers in your selected region.
• All pages and tabs can now be bookmarked, allowing you to return to or share pages of interest easily.
• Phenotype tree browser (based on MeSH) for retrieving Studies linked to one or more categories of Phenotype.
• Phenotype term search which will find Studies matching different variations on a term.

This study database release (v4) provides 60 additional GWAS studies and 4 GWAS updated studies that can be viewed in the HGVbaseG2P browser. 53 GWAS studies were imported from:

1. NHGRI GWAS Catalog
2. Seven other publications

Four studies (HGVST27, HGVST58, HGVST83 and HGVST185) were updated with additional marker information.

The Human Gene Mutation Database (HGMD) contains published mutations responsible for human inherited disease. HGMD data are visible in the browser, within the region view.

* HGMD Web Site
* HGMD Disclaimer

Release of 186 additional GWAS studies from:

1. NHGRI GWAS Catalogue
2. An Open Access Database of Genome-wide Association Results

This brings the number of GWAS studies available in HGVbaseG2P to 305 with 291 available for analysis in the HGVbaseG2P browser.

Multiple studies can now be compared using our sophisticated new browser. We have also extended the database with data from over a hundred new studies:

1. NHGRI GWAS Catalogue
2. An Open Access Database of Genome-wide Association Results

This release (v2.2) provides tools to create and view marker reports containing:

1. The most significant markers in a single study through the studies list and individual study reports.
2. The most significant markers in selected studies through the browser.
3. All markers used in selected studies within a region of interest, using our browser Region View.

Additional refinements to visualisation tools. This includes instant access to Genome Views in a Study (with a switchable linear or log based scale), improved gene information in the genome region view and easy access to significance and display settings.

The graphical display of association signals in HGVbaseG2P has been made more powerful and informative via a new approach to data visualisation that presents information in genome-wide and chromosomal contexts, as well as at higher resolution alongside gene maps. Data presentation parameters are customisable so that users can graphically explore datasets to locate biologically significant regions and markers.