GWAS data release August 2014

August 17th, 2014 | Posted by rkh7 in News | Release | StudyRelease | Uncategorized - (Comments Off on GWAS data release August 2014)

GWAS Central has released over 200 additional GWAS.

New GWAS Central database released with significant additional content

September 5th, 2013 | Posted by rkh7 in News | Release | StudyRelease | Uncategorized - (Comments Off on New GWAS Central database released with significant additional content)

GWAS Central Study database release 11 is released 5th September 2013

Version 11  of the study database includes significant new content increasing the number of GWAS from 1008 (34,131,526 p-values) to 1,605 studies (67,723,637 p-values, 2,935163 unique dbSNP markers). All phenotypes included in the studies have been annotated to MeSH controlled vocabulary with direct mappings to Human Phenotype Ontology (HPO) where available.

Version 11 includes data from:

NHGRI GWAS Catalog
Open Access Database of Genome-wide Association Results,
Japanese GWASdb
dbGaP
WTCCC
Broad
CGEMS
1958 British Birth Cohort
Magic Consortium
Spiro Consortium
Giant Consortium

Studies from publication supplementary data

Direct Submissions to GWAS Central including submissions from contacting study owners

GWAS Mart Tutorial available

September 5th, 2013 | Posted by rkh7 in News | Uncategorized - (Comments Off on GWAS Mart Tutorial available)

A short tutorial on how to use the GWAS Mart is now available in the Help section of the website.

Please see the following page for further details:

http://www.gwascentral.org/info/how-to/how-to-use-gwas-mart/

GWAS Central database summary updated in NAR Molecular Biology Database Collection

July 23rd, 2013 | Posted by rkh7 in News | Uncategorized - (Comments Off on GWAS Central database summary updated in NAR Molecular Biology Database Collection)

GWAS Central database summary updated in NAR Molecular Biology Database Collection highlighting developments from the past year

http://www.oxfordjournals.org/nar/database/summary/131

Semantically enabling a genome-wide association study database

July 17th, 2013 | Posted by rkh7 in News | Uncategorized - (Comments Off on Semantically enabling a genome-wide association study database)

Semantically enabling a genome-wide association study database: a publication using data from GWAS Central describing a methodology for applying phenotype annotations to a comprehensive genome-wide association dataset and for ensuring compatibility with the Semantic Web was published December 2012.

The provision of GWAS nanopublications enables a new dimension for exploring GWAS data, by way of intrinsic links to related data resources within the Linked Data web. The value of such annotation and integration will grow as more biomedical resources adopt the standards of the Semantic Web.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579732/

The GWAS Central phenotype annotations can be queried and viewed from the web interface at:

http://www.gwascentral.org/phenotypes

The GWAS Central SPARQL end-point can be accessed at:

http://fuseki.gwascentral.org

The human-mouse comparative phenotype pipeline described in this paper, named “get human and mouse phenotypes for a gene”, is available from myExperiment at:

http://www.myexperiment.org/workflows/2131.html

 

Semantic Web/Linked Data support added

April 2nd, 2012 | Posted by rcf8 in News | Uncategorized - (Comments Off on Semantic Web/Linked Data support added)

GWAS Central now provides data in Semantic Web and Linked Data compatible formats through:

  • Individual markers, phenotypes and results which now output RDF and Turtle formats that connect to Linked Data resources.
  • Nanopublications: a  Semantic Web resource using named graphs, and contain key results for each dataset outputs N-Quads format. These follow the nanopublication proposals suggested here.
  • The construction of a triple-store with a SPARQL server available at http://fuseki.gwascentral.org.

We are in the process of updating the Web Services section of our help with more information.

Updated Data Sharing Statement

April 2nd, 2012 | Posted by rcf8 in News | Uncategorized - (Comments Off on Updated Data Sharing Statement)

GWAS Central is committed to data sharing wherever possible, to maximise the value and scientific impact of data. However, this has to balanced against the risk of identifying research subjects (see Homer et al: http://dx.doi.org/10.1371/journal.pgen.1000167). Additionally, data in GWAS Central are curated and integrated, making them unique as an asset. For these reasons, our policy on data sharing is that we openly provide large amounts of data (up to 1,000 markers and associated data per download), in a range of displays and formats, sufficient for the needs of most researchers. Complete downloads of the complete database, or very large segments of it, are not openly allowed, but can be discussed in special cases that do not involve competing projects or commercial use of the data.

GWAS Central improved and revamped

March 9th, 2012 | Posted by rkh7 in News | Uncategorized - (Comments Off on GWAS Central improved and revamped)

GWAS Central version 6 has been released with the following new features:

  • Website redesign and revamped cleaner user interface with improved search.
  • Separate gene/region search to simplify finding data related to a gene or region.
  • Updated MeSH to 2012 version.
  • GWAS Mart data mining tool integrated into site through canned queries and GWAS Mart section.
  • Human genome build 37 support (new versions of HGMD data, UCSC genes, HapMap data liftover and updating the GWAS Central marker catalogue and association database).

New version of GWAS Central with improved news, help and information pages

March 16th, 2011 | Posted by rcf8 in News | Uncategorized - (Comments Off on New version of GWAS Central with improved news, help and information pages)

GWAS Central version 5.0 has improved news articles, extended online help (including screenshots and extra links where appropriate) and additional information related to more technical aspects of the system such as our web-services.

HGVbaseG2P is now GWAS Central!

February 22nd, 2011 | Posted by tb143 in News | Uncategorized - (Comments Off on HGVbaseG2P is now GWAS Central!)

GWAS Central is the new name for HGVbaseG2P, a comprehensive resource of summary-level genome-wide association studies

We still provide all the features of the old HGVbaseG2P site but with a new user friendly name. All book marked URLs will still work but you will be redirected to GWAS Central. We are still using all previous naming conventions from HGVbaseG2P.

As of February 20011 we have re-launched with a new release of the old HGVbaseG2P study database (release 9). The new GWAS Central study database (release 10) includes 708 studies:

  • 143 imported GWAS from NHGRI GWAS Catalog
  • Supplementary data from the WTCCC paper PMID:17554300 (HGVST7-HGVST13)